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Osteoarthritis Research Laboratory

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Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes
  • AuthorHuh YH, Kim SH, Kim SJ, Chun JS
  • Year2002
  • SourceJ Biol Chem. 2003 Mar 14;278(11):9691-7. Epub 2002 Dec 18. Related Articles, Links

Regulation of the chondrocyte phenotype by beta-catenin.
  • AuthorRyu JH, Kim SJ, Kim SH, Oh CD, Hwang SG, Chun CH, Oh SH, Seong JK, Huh TL, Chun JS.
  • Year2002
  • SourceDevelopment. 2002 Dec;129(23):5541-50. Related Articles, Links

Beta-catenin regulates expression of cyclooxygenase-2 in articular chondrocytes
  • AuthorKim SJ, Im DS, Kim SH, Ryu JH, Hwang SG, Seong JK, Chun CH, Chun JS.
  • Year2002
  • SourceBiochem Biophys Res Commun. 2002 Aug 9;296(1):221-6. Related Articles, Links

p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B-dependent transcription and stabilization by serine 15 phosphorylation.
  • AuthorKim SJ, Hwang SG, Shin DY, Kang SS, Chun JS.
  • Year2002
  • SourceJ Biol Chem. 2002 Sep 6;277(36):33501-8. Epub 2002 Jun 28. Related Articles, Links

p38 kinase-dependent and -independent Inhibition of protein kinase C zeta and -alpha regulates nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes.
  • AuthorKim SJ, Kim HG, Oh CD, Hwang SG, Song WK, Yoo YJ, Kang SS, Chun JS.
  • Year2002
  • SourceJ Biol Chem. 2002 Aug 16;277(33):30375-81. Epub 2002 Jun 4. Related Articles, Links

Maintenance of differentiated phenotype of articular chondrocytes by protein kinase C and extracellular signal-regulated protein kinase.
  • AuthorYoon YM, Kim SJ, Oh CD, Ju JW, Song WK, Yoo YJ, Huh TL, Chun JS.
  • Year2002
  • SourceJ Biol Chem. 2002 Mar 8;277(10):8412-20. Epub 2001 Dec 14. Related Articles, Links

ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status.
  • AuthorKim SJ, Ju JW, Oh CD, Yoon YM, Song WK, Kim JH, Yoo YJ, Bang OS, Kang SS, Chun JS.
  • Year2002
  • SourceJ Biol Chem. 2002 Jan 11;277(2):1332-9. Epub 2001 Oct 31. Related Articles, Links

Immunosuppressant rapamycin inhibits protein kinase C alpha and p38 mitogen-activated protein kinase leading to the inhibition of chondrogenesis.
  • AuthorOh CD, Kim SJ, Ju JW, Song WK, Kim JH, Yoo YJ, Chun JS.
  • Year2001
  • SourceEur J Pharmacol. 2001 Sep 21;427(3):175-85. Related Articles, Links

Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity.
  • AuthorYoon JB, Kim SJ, Hwang SG, Chang S, Kang SS, Chun JS
  • Year20003
  • SourceJ Biol Chem. 2003 Apr 25;278(17):15319-25. Epub 2003 Feb 14. Related Articles, Links

Disruption of actin cytoskeleton induces chondrogenesis of mesenchymal cells by activating protein kinase C-alpha signaling.
  • AuthorLim YB, Kang SS, Park TK, Lee YS, Chun JS, Sonn JK.
  • Year2000
  • SourceBiochem Biophys Res Commun. 2000 Jul 5;273(2):609-13. Related Articles, Links
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