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Osteoarthritis Research Laboratory

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Total 74 , Page 3 / 8

NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis.
  • Year2013
  • SourceAnn Rheum Dis doi:10.1136/annrheumdis-2013-204355

Dickkopf-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.
  • Year2012
  • SourceArthritis Rheum. 2012 Aug;64(8):2568-78. doi: 10.1002/art.34481

Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.
  • Year2012
  • SourceJ Bone Miner Res. 2012 Mar 9. doi: 10.1002/jbmr.1583.

α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex
  • AuthorRhee J, Ryu JH, Kim JH, Chun CH, Chun JS.
  • Year2012
  • SourceJ Biol Chem. 2012 Apr 6;287(15):11751-60. Epub 2012 Feb 1

Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction.
  • Year2012
  • SourceCell Death Differ. 2012 Mar;19(3):440-50. doi: 10.1038/cdd.2011.111. Epub 2011 Aug 26

Cytokine-like 1 knock-out mice (Cytl1-/-) show normal cartilage and bone development but exhibit augmented osteoarthritic cartilage destruction.
  • Year2011
  • SourceJ Biol Chem. 2011 Aug 5;286(31):27206-13. Epub 2011 Jun 7

Interleukin 6 plays an essential role in hypoxia-inducible factor-2α-induced experimental osteoarthritic cartilage destruction in mice. Arthritis Rheum.
  • Year2011
  • SourceArthritis Rheum. 2011 May 16

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
  • Year2010
  • SourceNat Med. 2010 Jun;16(6):687-93. Epub 2010 May 23

In vitro chondrocyte culture in a heparin-based hydrogel for cartilage regeneration. Tissue Eng Part C Methods.
  • Year2010
  • SourceTissue Eng Part C Methods. 2010 Feb;16(1):1-10.

Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction.
  • Year2009
  • SourceGene. 2009 Dec 1;448(1):7-15. Epub 2009 Sep 6.
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