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Osteoarthritis Research Laboratory

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Overexpression of secretory leukocyte peptidase inhibitor (SLPI) does not modulate experimental osteoarthritis but may be a biomarker for the disease.
  • AuthorKim HE, Shin Y, Jung I, Yang JI, Chun CH, Kim HA, Chun JS
  • Year2021
  • SourceOsteoarthritis Cartilage. 2021 Apr

Upregulated endonuclease Regnase-1 suppresses osteoarthritis by forming a negative feedback loop of catabolic signaling in chondrocytes.
  • AuthorYang JI, Chun JS
  • Year2021
  • SourceArthritis Res Ther. 2021 Apr

ZIP8 exacerbates collagen-induced arthritis by increasing pathogenic T cell responses.
  • AuthorKang JA, Kwak JS, Park SH, Sim KY, Kim SK, Shin Y, Jung IJ, Yang JI, Chun JS, Park SG
  • Year2021
  • SourceExp Mol Med. 2021 Apr

LBP and CD14, cofactors of toll-like receptors, are essential for low-grade inflammation-induced exacerbation of post-traumatic osteoarthritis.
  • AuthorWon Y, Yang JI, Park S, Chun JS
  • Year2021
  • SourceArthritis Rheumatol. 2021 Feb

CYTL1 regulates bone homeostasis in mice by modulating osteogenesis of mesenchymal stem cells and osteoclastogenesis of bone marrow-derived macrophages.
  • Year2019
  • SourceCell Death Dis. 2019 Jan

RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family.
  • Year2019
  • SourceNat Commun. 2019 Jan

Critical role for arginase II in osteoarthritis pathogenesis.
  • Year2019
  • SourceAnn Rheum Dis. 2019 Mar

The CH25H-CYP7B1-RORα axis of cholesterol metabolism regulates osteoarthritis.
  • Year2019
  • SourceNature. 2019 Feb

BATF regulates collagen-induced arthritis by regulating T helper cell differentiation.
  • Year2018
  • SourceArthritis Res Ther. 2018 Aug

Estrogen-related receptor γ is a novel catabolic regulator of osteoarthritis pathogenesis
  • Year2018
  • SourceBMB Rep. 2018 Jan
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